In the Andean countries, mining has been an important factor in reducing poverty and inequality, but has also resulted in negative human rights impacts, socio-environmental conflicts and environmental pollution. The German Federal Ministry for Economic Cooperation and Development (BMZ) commissioned GIZ and the Federal Institute for Geosciences and Natural Resources (BGR) to implement the Regional Cooperation for the sustainable management of mineral resources in the Andean countries Programme (MinSus) from 2014 until 2022. The programme aims at supporting Andean countries in designing and implementing sustainable mining practices, as well as promoting transparency along mineral supply and value chains. This Promising Practice describes the measures implemented by the project, its impact and lessons learned.